Radiocirurgia robótica no tratamento de paragangliomas do osso temporal: experiência de um centro e revisão da literatura

Sofia Ramos; Sara Simões; Marina Amorim; Maria Adelina Costa; Guilherme Campos; Graça Fonseca; Miguel Carvalho; Pedro Vieira; Cármen Calçada; Paulo Serafim Costa

doi:10.34631/sporl.2092

Autores

Sofia Ramos Serviço de Radioterapia do Hospital de Braga, Portugal https://orcid.org/0000-0002-5096-6490
Sara Simões Serviço de Radioterapia do Hospital de Braga, Portugal https://orcid.org/0009-0007-3473-7149
Marina Amorim Serviço de Radioterapia do Hospital de Braga, Portugal https://orcid.org/0000-0001-5693-4855
Maria Adelina Costa Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0000-0002-4599-6679
Guilherme Campos Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0000-0001-8923-6412
Graça Fonseca Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0009-0001-2563-3221
Miguel Carvalho Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0009-0005-6001-955X
Pedro Vieira Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0009-0004-4772-218X
Cármen Calçada Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0009-0002-8300-659X
Paulo Serafim Costa Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal

DOI:

https://doi.org/10.34631/sporl.2092

Palavras-chave:

Paraganglioma, Cyberknife, Radiocirurgia

Resumo

Objetivo: Reportar a experiência de um centro no tratamento de paragangliomas do osso temporal com radiocirurgia robótica.
Desenho do Estudo: Análise retrospetiva unicêntrica
Material e Métodos: Entre 2017 e 2021, 8 doentes com paragangliomas do osso temporal receberam tratamento com Cyberknife no Serviço de Radioterapia do Instituto CUF Porto.
Resultados: Metade dos doentes apresentavam recidiva tumoral após cirurgia +/- embolização. O tempo de seguimento médio foi de 33 meses. Relativamente à resposta clínica, 4 doentes melhoraram dos sintomas pré-radiocirurgia, 2 mantiveram-se assintomáticos e 2 apresentaram estabilidade neurológica. Todos os tumores revelaram regressão (n=5) ou estabilidade dimensional (n=3) - seguimento com ressonância magnética (RM), com um controlo local de 100%. Não foi reportada toxicidade aguda grau ≥3 ou tardia.
Conclusões: Na presente análise, a radiocirurgia robótica parece demonstrar ser uma abordagem terapêutica útil na gestão dos paragangliomas do osso temporal, quer nas recidivas após cirurgia e/ou embolização, quer como tratamento radical único.

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Radiocirurgia robótica no tratamento de paragangliomas do osso temporal: experiência de um centro e revisão da literatura

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