Radiocirurgia robótica no tratamento de paragangliomas do osso temporal: experiência de um centro e revisão da literatura

Sofia Ramos; Sara Simões; Marina Amorim; Maria Adelina Costa; Guilherme Campos; Graça Fonseca; Miguel Carvalho; Pedro Vieira; Cármen Calçada; Paulo Serafim Costa

doi:10.34631/sporl.2092

Authors

Sofia Ramos Serviço de Radioterapia do Hospital de Braga, Portugal https://orcid.org/0000-0002-5096-6490
Sara Simões Serviço de Radioterapia do Hospital de Braga, Portugal https://orcid.org/0009-0007-3473-7149
Marina Amorim Serviço de Radioterapia do Hospital de Braga, Portugal https://orcid.org/0000-0001-5693-4855
Maria Adelina Costa Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0000-0002-4599-6679
Guilherme Campos Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0000-0001-8923-6412
Graça Fonseca Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0009-0001-2563-3221
Miguel Carvalho Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0009-0005-6001-955X
Pedro Vieira Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0009-0004-4772-218X
Cármen Calçada Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal https://orcid.org/0009-0002-8300-659X
Paulo Serafim Costa Serviço de Radioterapia Júlio Teixeira SA, Instituto CUF, Porto, Portugal

DOI:

https://doi.org/10.34631/sporl.2092

Keywords:

Paraganglioma, Cyberknife, Radiosurgery

Abstract

Objective: To report the experience of a single center in the treatment of temporal bone paragangliomas with Robotic Radiosurgery.
Study Design: Single-center retrospective analysis
Material and Methods: Between 2017 and 2021, 8 patients with temporal bone paragangliomas were treated with Cyberknife in the Department of Radiation Oncology of Instituto CUF Porto.
Results: Half of the patients were diagnosed with recurrent tumors after surgery +/- embolization. The median follow-up was 33 months. Regarding clinical outcomes, 4 patients showed improvement in pre-radiosurgery symptoms, 2 remained symptom-free and 2 demonstrated neurological stability. All tumors revealed regression (n=5) or stable dimension (n=3) during follow-up MRI, with local control of 100%. There was no grade ≥3 or late toxicities.
Conclusion: Robotic Radiosurgery seems to be a helpful therapeutic approach in the management of temporal bone paragangliomas, either after surgery and/or embolization recurrences or as a single and radical treatment.

References

Tosun İ, Atalar B, Şahin B, Güngör G, Aydin G, Yapici B. et al. Robotic radiosurgery of head and neck paragangliomas: a single institution experience. Asia Pac J Clin Oncol [Internet]. 2018 Apr [cited 2023 Jul 24];14(2):e3–7. Available from: https://onlinelibrary.wiley.com/doi/10.1111/ajco.12695

Weissmann T, Lettmaier S, Roesch J, Mengling V, Bert C, Iro H. et al. Paragangliomas of the head and neck: local control and functional outcome following fractionated stereotactic radiotherapy. Am J Clin Oncol [Internet]. 2019 Nov [cited 2023 Jul 24];42(11):818–23. Available from: https://journals.lww.com/10.1097/COC.0000000000000614

Anderson JL, Khattab MH, Anderson C, Sherry AD, Luo G, Manzoor N, et al. Long-term outcomes for the treatment of paragangliomas in the upfront, adjuvant, and salvage settings with stereotactic radiosurgery and intensity-modulated radiotherapy. Otol Neurotol [Internet]. 2020 Jan [cited 2023 Jul 24];41(1):133–40. Available from: https://journals.lww.com/10.1097/MAO.0000000000002461

Fatima N, Pollom E, Soltys S, Chang SD, Meola A. Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis. Neurosurg Rev [Internet]. 2021 Apr [cited 2023 Jul 24];44(2):741–52. Available from: https://link.springer.com/10.1007/s10143-020-01292-5

Dharnipragada R, Butterfield JT, Dhawan S, Adams ME, Venteicher AS. Modern management of complex tympanojugular paragangliomas: systematic review and meta-analysis. World Neurosurg [Internet]. 2023 Feb [cited 2023 Jul 24];170:149-156.e3. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1878875022015893

Mendenhall WM, Morris CG, Amdur RJ, Hitchcock KE, Silver NL, Dziegielewski PT. Radiotherapy for benign head and neck paragangliomas. Head Neck [Internet]. 2019 Jul [cited 2023 Jul 24];41(7):2107–10. Available from: https://onlinelibrary.wiley.com/doi/10.1002/hed.25664

Ehret F, Kufeld M, Fürweger C, Haidenberger A, Schichor C, Tonn J. et al. Single‐session image‐guided robotic radiosurgery and quality of life for glomus jugulare tumors. Head Neck [Internet]. 2020 Sep [cited 2023 Jul 24];42(9):2421–30. Available from: https://onlinelibrary.wiley.com/doi/10.1002/hed.26231

Lior U, Rotem H, Uzi N, Roberto S. LINAC radiosurgery for glomus jugulare tumors: retrospective – cohort study of 23 patients. Acta Neurochir (Wien) [Internet]. 2020 Apr [cited 2023 Jul 24];162(4):839–44. Available from: http://link.springer.com/10.1007/s00701-020-04251-7

Maxwell AK, Mehta GU, Muelleman T, Barnard ZR, Hartwick T, Mak A. et al. Hypofractionated robotic stereotactic radiosurgery for vagal paragangliomas: a novel treatment strategy for cranial nerve preservation. Otolaryngol Head Neck Surg. [Internet]. 2020 Jun [cited 2023 Jul 24];162(6):897–904. Available from: https://onlinelibrary.wiley.com/doi/10.1177/0194599820910150

Ong V, Bourcier AJ, Florence TJ, Mozaffari K, Mekonnen M, Sheppard JP. et al. Stereotactic radiosurgery for glomus jugulare tumors: systematic review and meta-analysis. World Neurosurg. [Internet]. 2022 Jun [cited 2023 Jul 24];162:e49–e57. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1878875022001905

Bianchi LC, Marchetti M, Brait L, Bergantin A, Milanesi I, Broggi G. et al. Paragangliomas of head and neck: a treatment option with CyberKnife radiosurgery. Neurol Sci [Internet]. 2009 Dec [cited 2023 Jul 24];30(6):479–85. Available from: http://link.springer.com/10.1007/s10072-009-0138-3

Hong S, Kagawa K, Sato K, Ichi S. The long-term outcome of cyberKnife-based stereotactic radiotherapy for head and neck paragangliomas: a single-center experience. World Neurosurg. [Internet]. 2021 Nov [cited 2023 Jul 24];155:e382–90. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1878875021012377

Patel AK, Rodríguez‐López JL, Hirsch BE, Burton SA, Flickinger JC, Clump DA. Long term outcomes with linear accelerator stereotactic radiosurgery for treatment of jugulotympanic paragangliomas. Head Neck [Internet]. 2021 Feb [cited 2023 Jul 24];43(2):449–55. Available from: https://onlinelibrary.wiley.com/doi/10.1002/hed.26497

Ko CC, Yeh LR, Kuo YT, Chen JH. Imaging biomarkers for evaluating tumor response: RECIST and beyond. Biomark Res [Internet]. 2021 Dec [cited 2023 Jul 31];9(1):52. Available from: https://biomarkerres.biomedcentral.com/articles/10.1186/s40364-021-00306-8

Rougier G, Rochand A, Bourdais R, Meillan N, Tankere F, Herman P, et al. Long‐term outcomes in head and neck paragangliomas managed with intensity‐modulated radiotherapy. Laryngoscope [Internet]. 2023 Mar [cited 2023 Jul 24];133(3):607–14. Available from: https://onlinelibrary.wiley.com/doi/10.1002/lary.30226

Sahyouni R, Mahboubi H, Moshtaghi O, Goshtasbi K, Sahyouni S, Lin HW. et al. Radiosurgery of glomus tumors of temporal bone: a meta-analysis. Otol Neurotol. [Internet]. 2018 Apr [cited 2023 Jul 24];39(4):488–93. Available from: https://journals.lww.com/00129492-201804000-00022

Sallabanda K, Barrientos H, Isernia Romero DA, Vargas C, Gutierrez Diaz JA, Peraza C. et al. Long-term outcomes after radiosurgery for glomus jugulare tumors. Tumori [Internet]. 2018 Aug [cited 2023 Jul 24];104(4):300–6. Available from: http://journals.sagepub.com/doi/10.1177/0300891618765576

Robotic radiosurgery for temporal bone paragangliomas: single-center experience and review of the literature

Authors

DOI:

Keywords:

Abstract

References

Downloads

Published

How to Cite

Issue

Section

License

sociedade

Language

index