Primitive neuroectodermic tumor: case report
DOI:
https://doi.org/10.34631/sporl.272Keywords:
PNET, primitive neuroectodermal tumors, Ewing's sarcomaIPNET, peripheral PNETAbstract
Primitive neuroectodermal tumors (PNET) are a group of highly aggressive tumors which are rare in the head and neck region. There are several prognostic factors but one of the most important is the presence or absence of metastatic disease.
The treatment must be aggressive, as the use of chemotherapy regimens has significantly improved outcomes in these patients. The authors present a clinical case of a patient with a peripheral primitive neuroectodermal tumor (EwingI PNET Group) located in the nasopharynx and paranasal sinuses.
References
Batsakis JG, Mackay B, el-Naggar AK e al. Ewing's sarcoma and peripheral primitive neuroectodermal tumor: an interim report. Ann Otol Rhinol Laryngol. Oct 1996;105(10):838-43
Dehner LP. Primitive neuroectodermal tumor and Ewing's sarcoma. Am J Surg Pathol 1993;17:1-13
Dehner LP. Peripheral and central primitive neuroectodermal tumors: A noso- logic concept seeking a consensus. Arch Pathol Lab Med 1986;110:997-1005 4.Grier HE. The Ewing family of tumors. Ewing's sarcoma and primitive neuroectodermal tumors. Pediatr Clin North Am 1997;44:991-1004
Shishikura A, Ushigome S, Shimoda T. Primitive neuroectodermal tumors of bone and soft tissue: Histological subclassification and clinicopathologic correlations. Acts Pathol Jpn 1993;43:176-86
Franchi A, Pasquinelli G, Cenacchi G et al. Immunohistochemical and ultrastructural investigation of neural differentiation in Ewing sarcoma/ PNET of bone and soft tissues. Ultrastruct Pathol. 2001 May-Jun;25{3):219-25
Llombart-Boseh A, Terrier Lacombe MJ, Peydro-Olaya A, Contesso G. Peripheral neuroectodermal sarcoma of soft tissue (peripheral neuroepithelioma): A pathologic study of ten cases with differential diagnosis regarding other small, round-cell sarcomas. Hum Pathol 1989;20:273-80
Marina NM, Etcubanas E, Parham DM et al. Peripheral primitive neuroecto- dermal tumor (peripheral neuroepithelioma) in children. A review of the St. Jude experience and controversies in diagnosis and management. Cancer 1989;64:1952-60
Jones JE, McGill T. Peripheral primitive neuroectodermal tumors of the head and neck. Arch Otolaryngol Head Neck Surg. Dec 1995; 121(12):392-5
Jurgens H, Bier V, Harms D et al. Malignant peripheral neuroectodermal tumors. A retrospective analysis of 42 patients. Cancer. Jan 15 1988;61(2):349-57
Kushner BH, Hajdu SI, Gulati SC et al. Extracranial primitive neuroectodermal tumors: The Memorial Sloan-Kettering Cancer Center experience. Cancer 1991;67:1825-9
