Rosai-Dorfman disease with exclusive nasal involvement: Case report
DOI:
https://doi.org/10.34631/sporl.774Keywords:
Rosai-Dorfman Disease, Nose, Paranasal SinusesAbstract
Rosai-Dorfman disease is a histiocytosis classically characterized by painless cervical lymphadenopathy. Nevertheless, in 43% of cases it may involve extranodal sites. It is an entity with a high clinical variability that can evolve from a self-limited episode to death.
A 64-year-old female with complains of nasal obstruction presented on the physical examination a septum deviation and nasal polyposis grade III bilaterally. A computed tomography was requested and highlighted an almost complete opacification of the paranasal sinuses, as well as signs of bone erosion. The patient underwent endoscopic sinus surgery. The cyto-histopathological examination revealed Rosai-Dorfman disease. Laboratory tests and imaging study were performed and allowed the exclusion of primary pathology and other sites of the disease.
This case was particularly interesting because of the surgical challenge it posed, since the disease caused a significant alteration in the nasal anatomy.
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