Two forms of amyloidosis presentation in ENT
DOI:
https://doi.org/10.34631/sporl.94Keywords:
systemic amyloidosis, localized amyloidosis, macroglossia, larynxAbstract
Objective: To report two cases of amyloidosis with clinical
presentation in Otolaryngology, as well as a theoretical review
about its pathology, including clinical presentation, diagnosis
and therapeutic options.
Methods: A retrospective study was made with two cases of
amyloidosis diagnosed in our department between 2003 and
2010. We present a case of primary systemic amyloidosis
associated with Multiple Myeloma, with presentation in
Otolaryngology, and a second case of localized amyloidosis in
the larynx.
Results: Amyloidosis, either in its localized or systemic form, is
relatively rare in Otolaryngology. However, macroglossia is a
common symptom of systemic amyloidosis, occurring in up to
20% of patients. The localized amyloidosis primarily affects the
larynx, thus being of great importance to the otolaryngologist.
Conclusions: Amyloidosis should be part of the differential
diagnosis in head and neck lesions, with mandatory exclusion
of its systemic form.
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