Descending Necrotizing Mediastinitis: Case analysis from the last years

Authors

DOI:

https://doi.org/10.34631/sporl.3061

Keywords:

Descending necrotizing mediastinitis, transcervical drainage, transthoracic drainage, video-assisted thoracic surgery

Abstract

Objectives: To describe the experience of approaching cases of Descending Necrotizing Mediastinitis (DNM) over the last 3 years in a tertiary hospital, addressing therapeutic approaches, results and complications.

Methods: A descriptive retrospective study from November 2019 to December 2022, evaluating 7 patients diagnosed with DNM. Analysis included age, gender, disease subtype, clinical presentation, infection origin, comorbidities, surgical interventions, hospitalization duration, and isolated microorganisms.

Results: All patients underwent surgery for drainage of collections and surgical debridement. The majority of patients (85.7%) underwent combined transcervical and transthoracic drainage. Only one patient underwent isolated transcervical surgical approach. Five cases (71.4%) required reoperation/surgical revision. Tracheostomy was performed in 57.1% of cases. The average hospitalization duration was 52.1 ± 33.6 days (range: 23-120 days), while the average intensive care unit stay was 22 ± 26.6 days (range: 2-77 days). No deaths occurred during hospitalization, and only one patient experienced complications, namely pneumonia and bilateral vocal cord immobility, requiring permanent tracheostomy. The remaining patients were discharged with a favorable outcome.

Conclusion: To improve the prognosis of DNM, early and appropriate surgical debridement of affected areas, along with targeted antibiotics and/or antifungals, is essential. A multidisciplinary approach involving Cardiothoracic Surgery and Otolaryngology is indispensable for the treatment of this condition.

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Published

2025-03-02

How to Cite

Lourenço Marques, D., Bartolomeu, F., Figueiredo, H., Rato, C., Paiva, S., Miguéis, A., & Miguéis, J. (2025). Descending Necrotizing Mediastinitis: Case analysis from the last years. Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery, 63(1), 483–494. https://doi.org/10.34631/sporl.3061

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Original Article