Cystic fibrosis: Relationship between sinus and lower airway disease

Authors

  • David Rodrigues Dias Centro Hospitalar Universitário do Porto EPE Porto, Portugal
  • Ana Nóbrega Pinto Centro Hospitalar Universitário do Porto EPE Porto, Portugal
  • Pedro Santos Centro Hospitalar Universitário do Porto EPE Porto, Portugal
  • Sandra Sousa Castro Centro Hospitalar Universitário do Porto EPE Porto, Portugal
  • Miguel Bebiano Coutinho Centro Hospitalar Universitário do Porto EPE Porto, Portugal
  • Cecília Almeida e Sousa Centro Hospitalar Universitário do Porto EPE Porto, Portugal

DOI:

https://doi.org/10.34631/sporl.888

Keywords:

Cystic Fibrosis, Chronic Rhinosinusitis

Abstract

Purpose: To evaluate the relationship between Chronic Rhinosinusitis (CRS) and lower airway disease (LAD) in cystic fibrosis (CF) patients. 

Material and Methods: Retrospective study of CF patients observed between January 2010 and December 2019 in our department. Lung function tests parameters, image studies, need for lung transplantation, colonization and hospitalization rates were collected and its association with the presence and severity of CRS was assessed. 

Results: 44 patients with mean aged 14.7 ±1.23 years old were analyzed. 59.1% had CRS, presenting a mean Lund-Mackay score of 8.38 (±6.4). CRS was associated with increased need for lung transplantation (p=0.04) and these patients presented a higher Lund-Mackay score (14.9±5.8 vs. 7.8±5.1, p=0.012). CRS did not influence lung function tests results. 

Conclusions: Sinus disease may influence lower airway disease prognosis in CF patients. 

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Published

2021-06-09

How to Cite

Rodrigues Dias, D., Nóbrega Pinto , A. ., Santos, P., Sousa Castro, S., Bebiano Coutinho, M., & Almeida e Sousa, C. (2021). Cystic fibrosis: Relationship between sinus and lower airway disease. Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery, 59(2), 153–157. https://doi.org/10.34631/sporl.888

Issue

Vol. 59 No. 2 (2021): June

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Original Article

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