Sinonasal adenocarcinoma - hospital de braga ent department expertise
DOI:
https://doi.org/10.34631/sporl.321Keywords:
Sinonasal adenocarcinoma, Endoscopic sinus surgery, Craniofacial resectionAbstract
Introduction: The nasal adenocarcinoma (AD) represents about 20% of cases of sinonasal malignancy. Endoscopic surgery (FESS) has gained preponderance for its treatment. In advanced stages, the craniofacial resection remain as an option, however the combined approach can be considered.
Objective and Methods: Retrospective analysis, between 2002 and 2014, of 14 AD cases diagnosed and treated in our department.
Results: The series consists of 14 patients with mean age of 60 years, and 11 with advanced stage at diagnosis. It was adopted, in 5 cases, an external surgical approach, in 6 FESS, and in 1 a combined approach. 5-years-overall- survival rate was 40%.
Conclusion: 2 and 5-years-survival rate is similar to other series already published.
References
- Lund V, Stammberger H, Nicolai P, Castelnouvo P, et. al. European Position Paper on Endoscopic Management of Tumours of the Nose, Paranasal Sinuses and Skull Base. Rhinology. Supplement 22. 2010.
- Lund V, Howard D, Wei W. Adenocarcinoma. In: Lund V, Howard D, Wei W (Eds.) Tumors of the nose, sinuses, and nasopharynx, Stuttgart, Thieme; 2014:pp137-50.
- Jégoux F, Métreau A, Louvel G, Bedfert C. Paranasal sinus câncer. Eur Ann Otorhinolaryngol Head Neck Dis. 2013 Dec;130(6):327-35.
- McMonagle BA, Gleeson M. 186 - Nasal cavity and paranasal sinus malignancy. In: Gleeson M, Browning GG, Burton MJ, Clarke R, et. al. (Eds.) Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery 7th edition. Vol.2. Great Britain, Hodder Arnold; 2008:pp2417-35.
- Pastore E, Perrone F, Orsenigo M, et. al. Polymorphisms of metabolizing enzymes and susceptibility to ethmoid intestinal-type adenocarcinoma in professionally exposed patients. Transl Oncol. 2009; 2(2):84-8.
- Gabory L, Maunoury A, Maurice-Tyson S, Abdulkhaleq HM, et. al. Long-Term Single-Center Results of Management of Ethmoid Adenocarcinoma: 95 Patients over 28 years. Ann Surg Oncol. 2010 Feb;17:1127-34.
- Sato Y, Morita M, Takahashi HO, Watanabe N, et. al. Combined Surgery, radiotherapy, and regional chemotherapy in carcinoma of the paranasal sinuses. Cancer. 1970 Mar;25(3):571-9.
- Knegt PP, Ah-See KW, Velden LA, Kerrebijn J. Adenocarcinoma of the ethmoidal sinus complex: surgical debulking and topical fluorouracil may be the optimal treatment. Arch Otolaryngol Head Neck Surg 2001;127(2):141-6.
- Airoldi M, Garzaro M, Valente G, et. al. Clinical and biological prognostic factos in 179 cases with sinonasal carcinoma treated in the Italian Piedmont region. Oncology 2009;76(4):262-9.
