Laryngeal paraganglioma
DOI:
https://doi.org/10.34631/sporl.10Keywords:
Laryngeal Paraganglioma, Laser CO2Abstract
Paragangliomas are neuroendocrine system tumors, with a low incidence in the head and neck. In the larynx, there are three distinct locations, the majority arise in the supraglottic larynx. They are considered benign tumors without metastatic capacity; the differential diagnosis with other neuroendocrine lesions is necessary, given the different therapeutic approaches. Surgical excision is considered the treatment of choice. Since the introduction of Laser CO2 surgery, some cases have been reported, but the degree of success is not standard. The authors present a case of supraglottic laryngeal paraganglioma in a 71 years old patient, that underwent a microlaryngoscopy with Laser CO2 excision. This therapeutic approach allowed tumor excision without tracheostomy, with follow up to three years without signs of local recurrence. Histology, immunohistochemistry and images obtained by contact endoscopy are documented and analyzed.
References
Pellitteri P, Rinaldo A, Myssiorek D, Ferlito et al. Paragangliomas of the head and neck. Oral Oncol 2004;40: 563-575
Myssiorek D, Rinaldo A, Barnes L, Ferlito A. Laryngeal Paraganglioma: An Updated Critical Review. Acta Otolaryngol 2004; 124: 995-999
Ferlito A, Devaney K, Rinaldo A. Neuroendocrine neoplasms of the larynx: Advances in identification, understanding, and management. Oral Oncology 2006;42:770-788
Sanders K, Abreo F, Rivera E, Stucker F et al. A diagnostic and Therapeutic Approach to Paragangliomas of the Larynx. Arch Otolaryngol Head Neck Surg. 2001;127:565-569
Francesco R, Sennes L, Tsuji D et al. Paraganglioma da Laringe. Revista Brasileira de ORL, 1997;63(3)
Papacharalampous G, Korres S, Tzagaroulakis et al. Paraganglioma of the larynx. Med Sci Monit, 2007;13(12):145-148
Gupta S, Pathak K, Sanghvi V. Transventricular paraganglioma of the larynx. Eur Arch Otorhinolaryngol 2003;260:358-360
Rubio V, Tamarit J, Baviera N, Estrems P et al. Laryngeal Paraganglioma: Diagnosis and Treatment. A propos of a case. Acta Otorrinolaringol Esp. 2007;58(7):333-4
Boedeker C, Ridder G, Schipper R. Paragangliomas of the head and neck: diagnosis and treatment. Familial Cancer 2005;4: 55-59
Smolarz J, Hanna E, Williams M, Kupferman M. Paraganglioma of the endolarynx: a rare tumor in an uncommon location. Head Neck Oncol 2010;2:2
Koopmans KP, Jager PL, Kema IP et al. 111In-octreotide is superior to 123I-metaiodobenzylguanidine for scintigrafhic detection of head and neck paragangliomas. J Nucl Med 2008;49(8):1232-7
Bustillo A, Telischi F, Weed D et al. Octreotide scintigraphy in the head and neck. Laryngoscope. 2004;114(3):434-40
