Implicaciones patogénicas de la reacción de fase aguda en sordera súbita idiopática
DOI:
https://doi.org/10.34631/sporl.72Keywords:
Sudden deafness, Acute phase reaction, Transient cerebral ischemiaAbstract
Introduction: Sudden deafness in most cases remains as an entity of unknown cause, although infectious, vascular and immune causes have been proposed.
Objectives: To study the relationship between the acute phase reaction in peripheral blood as an expression of transient cerebral ischemia in idiopathic sudden deafness.
Methods: Performing exploration ENT, tympanogram, audiometry, blood count, cranial MRI and neurological report.
Results: The acute phase inflammatory reaction is manifested as an increase in the rate of neutrophil / lymphocyte which appears 48-72 hours after the onset of sudden deafness.
Conclusions: The study shows that there is an acute phase inflammatory reaction in sudden deafness. On the other hand, the increased rate of neutrophil / lymphocyte discards the viral origin of sudden deafness. This knowledge and its objective determination help the understanding of the pathogenic mechanisms of sudden deafness.
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