Laryngeal Kaposi’s sarcoma - Case report
DOI:
https://doi.org/10.34631/sporl.201Keywords:
Kaposi sarcoma, larynx, HIV, AIDSAbstract
Kaposi’s sarcoma (KS), is the most common malignancy observed in the patient with acquired immune deficiency syndrome (AIDS). Head and neck involvement is not unusual. However laryngeal involvement with dyspnoea is rare. The authors present a clinical case that illustrates this pathology as the first manifestation of AIDS.
A 37 year-old male, with no prior pathology, with history of hoarseness, dysphagia and dyspnoea within 2 months. He presented with a supraglottic neoformation, and a biopsy of the lesion and a tracheotomy were performed. Complementary exams confirmed the diagnosis of laryngeal KS associated to human immunodeficiency virus (HIV) infection. He started chemotherapy, opportunistic infection prophylaxis and antiretroviral therapy. There was total regression of the lesions and he was decanulated after the 4th cyle of chemotherapy. This entity, rare as the initial manifestation of AIDS, must be considered in the differential diagnosis of laryngeal mass.
References
Ares C; Allal A.S. Long-term complete remission of laryngeal Kaposi’s sarcoma after palliative radiotherapy. Nature clinical practice oncology
; vol2: 473-477.
Choussy O; Haverbeke CV; Babin E; Francois A et al. Unusual presentation of oropharyngeal Kaposi Sarcoma. Head & Neck 2008;
: 411-415.
Angouridakis N; Constantinidis J; karkavelas G; Vlachtsis K et al. Classic (Mediterranean) Kaposi’s sarcoma of the true vocal cord: a
case report and review of the literature. Eur Arch Otorhinolaryngol 2006; 263: 537-540.
Watson J.R. Granoff D. Sataloff R.T. Dysphonia due to Kaposi’s Sarcoma as the Presenting Symptom Of Human Immunodeficiency
Virus. Journal of Voice 2004;18: 398-402.
Marsot-Dupuch K. Quilard J. Meyohas .M.C.Head and neck lesions in the immunocompromised host. Eur Radiol 2004; 14: 155-167.
Tahir J.M.; Gopalan KN; Marina MB; Putra SHA.P. A rare case of laryngeal kaposi’s sarcoma. Bangladesh Journal of Medical Science
; vol 9: 107-109.
Schiff N.F. Woo P. Annino D. J. Shapshay S.M. Kaposi’s sarcoma of the larynx. Ann Otol Rhinol Laryngol 1997; 106: 563-567.
Miner J.E.; Talmage D.E. An AIDS-Associated Cause of the Difficult Airway: Supraglottic Kaposi’s Sarcoma. Anesth Analg 2000; 90:1223-6.
Allison J.B. Ptaszynski K. Karpel J.P. Upper airway obstruction in a woman with AIDS-related Laryngeal Kaposi’s Sarcoma. Chest 1996;
:836-837.
Pantanowitz L,; Dezube B.J. Kaposi sarcoma in unusual locations. BMC Cancer 2008, 8:190.
