Kikuchi-Fujimoto disease: Differential diagnosis of cervical swelling

Authors

  • José Ferreira Penêda Centro Hospitalar Vila Nova de Gaia / Espinho http://orcid.org/0000-0001-8094-7728
  • Sandra Alves Centro Hospitalar Vila Nova de Gaia / Espinho
  • Rita Gama Centro Hospitalar Vila Nova de Gaia / Espinho
  • Joana Ferreira Centro Hospitalar Vila Nova de Gaia / Espinho
  • Nuno Barros Lima Centro Hospitalar Vila Nova de Gaia / Espinho
  • Artur Condé Centro Hospitalar Vila Nova de Gaia / Espinho

DOI:

https://doi.org/10.34631/sporl.745

Keywords:

Kikuchi-Fujimoto disease, Necrotizing histiocytic lymphadenitis, cervical adenopathy, cervical swelling

Abstract

Acquired cervical swelling is a common pathology that often motivates observation by Otorhinolaryngology. Its differential diagnosis is complex and encompasses inflammatory, infectious and neoplastic pathology. Kikuchi-Fujimoto disease is a benign and self-limited disease, rare in the Portuguese population. The diagnosis is unique and implies a high level of suspicion. The authors describe the case of a female patient who searched medical care due to a painful cervical swelling, with 6 days of evolution, without response to the treatment. Diagnostic challenge and treatment options are addressed. Keywords: Kikuchi-Fujimoto disease; Necrotizing histiocytic lymphadenitis; cervical adenopathy; cervical swelling.

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References

Antunes I, Botella A, Marques F, Araújo I, Abreu A, Cardiga R, et al. Dilemas de diagnóstico de linfadenite necrotizante. Acta Med Port. 2011;24(3):681–4.

Gaddey HL, Riegel AM, Bergquist E, Medicine F, Program R, Air O, et al. Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis. Am Fam Physician. 2016;94(11):896–903.

Dumas G, Prendki ÃV, Haroche J, Amoura Z, Cacoub P, Galicier L, et al. Kikuchi-Fujimoto Disease: Retrospective Study of 91 Cases and Review of the Literature. Medicine (Baltimore). 2014;93(24):372–82.

Kikuchi M. Lymphadenitis showing focal reticular cell hyperplasia with nuclear debris and phagocytes. Acta Hematol Jpn. 1972;35:379–80.

Fujimoto Y, Kozima Y, Yamaguchi K. Cervical subacute necrotizing lymphadenitis. Naika. 1972;30:920–7.

Bari A, Zeeshan F, Hanif G, Jabeen U, Bano I, Rathore A. A Rare Case of Kikuchi-Fujimoto Disease Associated with Systemic Lupus Erythematosus. J Coll Physicians Surg Pakistan. 2018;28(2):143–5.

Deaver D, Horna P, Cualing H, Sokol L. Pathogenesis , Diagnosis, and Management of Kikuchi–Fujimoto Disease. Cancer Control. 2014;21(4):313–21.

Pepe F, Disma S, Teodoro C, Pepe P, Magro G. Kikuchi-Fujimoto disease: a clinicopathologic update. Pathologica. 2015;107:120–9.

Mathew LM, Kapila R, Schwartz RA, Hon D, Edin F. Kikuchi–Fujimoto disease: a diagnostic dilemma. Int J Dermatol. 2016;(55):1069–75.

Lo KB, Papazoglou A, Chua L, Candelario N. Case Report: Kikuchi: The great mimicker. F1000Research. 2018;7(520):1–7.

Kim TY, Ha K, Kim Y, Lee J, Lee K, Lee J. Characteristics of Kikuchi – Fujimoto disease in children compared with adults. Eur J Pediatr. 2014;173:111–6.

Hu S, Kuo T, Hong H. Lupus lymphadenitis simulating Kikuchi’s lymphadenitis in patients with systemic lupus erythematosus: A clinicopathological analysis of six cases and review of the literature. Pathol Int. 2003;(53):221–6.

Ranabhat S, Tiwari M, Kshetri J, Maharjan S, Osti BP. An uncommon presentation of Kikuchi Fujimoto disease : a case report with literature review. BMC Res Notes. BioMed Central; 2015;8(478):1–4.

Published

2019-08-26

How to Cite

Penêda, J. F., Alves, S., Gama, R., Ferreira, J., Lima, N. B., & Condé, A. (2019). Kikuchi-Fujimoto disease: Differential diagnosis of cervical swelling. Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery, 56(4), 173–177. https://doi.org/10.34631/sporl.745

Issue

Section

Case Report