Severity predictors in severe idiopathic epistaxis: A retrospective review of hospitalized patients

Authors

  • Diogo Tomé Centro Hospitalar Universitário Lisboa Norte, Portugal https://orcid.org/0000-0002-5788-3639
  • Marta Canas Marques Centro Hospitalar Universitário Lisboa Norte, Portugal
  • Paulo Rocha Pereira Centro Hospitalar Universitário Lisboa Norte, Portugal
  • Marco Simão Centro Hospitalar Universitário Lisboa Norte, Portugal
  • Óscar Dias Centro Hospitalar Universitário Lisboa Norte, Portugal

DOI:

https://doi.org/10.34631/sporl.767

Keywords:

Epistaxis, Inpatients, Heart Disease, Type 2 Diabetes Mellitus

Abstract

Introduction: Studies have shown conflicting results about the risk factors of idiopathic epistaxis. The aim of this study is to identify predictors of severity in patients hospitalized with idiopathic epistaxis.

Study design: Observational, analytical, case-control, retrospective study.

Material and Methods: Data of 134 patients admitted over a period of 10 years, were collected. The sample was divided in two groups of severity. Univariate and multivariate analysis were performed to study the association between the severity of disease and potential predictors.

Results: “Very severe” disease occurred in 88 cases. The presence of heart disease was predictive of an increased risk of severe disease while diabetes was predictive of a decreased risk of severe disease.

Conclusions: Heart disease was predictive of increased severity of idiopathic epistaxis. In these patients, a premature evaluation by a Cardiologist should be considered. Curiously, type 2 diabetes mellitus was associated with decreased severity of idiopathic epistaxis.

References

- Davis R. Epistaxis: Medical vs. Surgical Therapy: A Comparison of Efficacy, Complications, and Economic Considerations. Arch Otolaryngol Head Neck Surg. 1987; 113(7):701-703. DOI:10.1288/00005537-198712000-00003

- Jackson K, Jackson R. Factors Associated With Active, Refractory Epistaxis. Arch Otolaryngol Head Neck Surg. 1988 Aug;114(8):862. Available from: https://www.ncbi.nlm.nih.gov/pubmed/3390329

- Klossek J, Dufour X, Montreuil C, Fontanel JP et al. Epistaxis and its management: an observational pilot study carried out in 23 hospital centres in France. Rhinology. 2006 Jun;44(2):151-5. Available from: https://www.ncbi.nlm.nih.gov/pubmed/16792176

- Pope L. Hobbs C. Epistaxis: an update on current management. Postgrad Med J. 2005 May; 81(955):309-314. DOI:10.1136/pgmj.2004.025007.

- Terakura M, Fujisaki R, Suda T, Sagawa T, Sakamoto T. Relationship between blood pressure and persistent epistaxis at the emergency department: a retrospective study. J Am Soc Hypertens. 2012 Jul-Aug;6(4):291-5. DOI:10.1016/j.jash.2012.05.001

- Page C, Biet A, Liabeuf S. Strunski V, Fournier A. Serious spontaneous epistaxis and hypertension in hospitalized patients. Eur Arch Otorhinolaryngol. 2011 Dec;268(12):1749-53. DOI:10.1007/s00405-011-1659-y.

- Smith J, Siddiq S, Dyer C, Rainsbury J, Kim D. Epistaxis in patients taking oral anticoagulant and antiplatelet medication: prospective cohort study. J Laryngol Otol. 2011 Jan;125(1):38-42. DOI:10.1017/S0022215110001921

- Fuchs F, Moreira L, Pires C, Torres FS et al. Absence of Association between Hypertension and Epistaxis: a Population-based Study. Blood Press. 2003; 12(3):145-148. Available from: https://www.ncbi.nlm.nih.gov/pubmed/12875475

- Lubianca Neto JF, Fuchs FD, Facco SR, Gus M, et al. Is epistaxis evidence of end-organ damage in patients with hypertension? Laryngoscope. 1999 Jul;109(7 Pt 1):1111-5. Available from: https://www.ncbi.nlm.nih.gov/pubmed/10401851.

- Ando Y, Iimura J, Arai S, Arai C et al. Risk factors for recurrent epistaxis: Importance of initial treatment. Auris Nasus Larynx. 2014 Feb;41(1):41-5.. DOI:10.1016/j.anl.2013.05.004

- Soyka M, Rufibach K, Huber A, Holzmann D. Is severe epistaxis associated with acetylsalicylic acid intake? Laryngoscope. 2010 Jan;120(1):200-7. DOI:10.1002/lary.20695

- Rainsbury J, Molony N. Clopidogrel versus low-dose aspirin as risk factors for epistaxis. Clin Otolaryngol. 2009 Jun; 34(3):232-235. DOI:10.1111/j.1749-4486.2009.01926.x

- Soyka M, Schrepfer T, Holzmann D. Blood markers of alcohol use in epistaxis patients. Eur Arch Otorhinolaryngol. 2012 Aug;269(8):1917-22. DOI:10.1007/s00405-011-1881-7

- Rejas Ugena E, Trinidad Ruiz G, Álvarez Domínguez J, Carrasco Claver F et al. Utilidad del tratamiento quirúrgico de la epistaxis grave mediante abordaje endoscópico de las arterias esfenopalatina y etmoidal anterior. Acta Otorrinolaringol Esp. 2006 May;57(5):228-234. DOI:10.1016/S0001-6519(06)78698-8

- McGarry GW. Epistaxis. In: Gleeson Michael (Ed) Scott-Brown's otorhinolaryngology, head and neck surgery, 7th ed. Abingdon, UK: Taylor & Francis; 2008. p 1596-1608.

- Mauer A, Khazanov N, Levenkova N, Tian S et al. Impact of sex, age, race, ethnicity and aspirin use on bleeding symptoms in healthy adults. J Thromb Haemost. 2011 Jan;9(1):100-8. DOI:10.1111/j.1538-7836.2010.04105.x

- Forbes J, Cooper M. Mechanisms of Diabetic Complications. Physiol Rev. 2013 Jan; 93(1):137-188. DOI:10.1152/physrev.00045.2011

- Chawla R, Chawla A, Jaggi S. Microvasular and macrovascular complications in diabetes mellitus: Distinct or continuum? Indian J Endocrinol Metab. 2016 Jul-Aug;20(4):546-51 DOI:10.4103/2230-8210.183480

Published

2019-11-24

How to Cite

Tomé, D., Canas Marques, M. ., Rocha Pereira, P., Simão, M., & Dias, Óscar. (2019). Severity predictors in severe idiopathic epistaxis: A retrospective review of hospitalized patients . Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery, 57(1), 11–15. https://doi.org/10.34631/sporl.767

Issue

Section

Original Article