Myoepithelioma of the Hard Palate - A Case report

Authors

  • Joana Borges da Costa Interna de formação específica da área de Otorrinolaringologia no Hospital Pedro Hispano
  • Diogo Abreu Pereira Interno de formação específica da área de Otorrinolaringologia no Hospital Pedro Hispano
  • Joana Santos Interna de formação específica da área de Otorrinolaringologia no Hospital Pedro Hispano
  • Delfim Duarte Diretor do Serviço de Otorrinolaringologia do Hospital Pedro Hispano
  • Gustavo Lopes Assistente Graduado de Otorrinolaringologia do Hospital Pedro Hispano

DOI:

https://doi.org/10.34631/sporl.786

Keywords:

myoepithelioma, salivary glands, hard palate

Abstract

Introduction: Myoepitheliomas (ME) are rare benign tumors that derive from ectodermal cells present in salivary glands (SG) and other secretory organs. These tumors usually affect the major GS and ME of minor GS are very rare. 

Case Report: We report a case of a 49-year-old patient referred to the Otorhinolaryngology consultation for progressive complaints of snoring with apnea since the last 4 months. The physical exam revealed a 2cm oval mass located in the right half of the hard palate. 

Imagiological exams confirmed the presence of a palatal mass without any signs of adjacent bone erosion. The lesion was surgically excised and histopathology showed a plasmacytoid myoepithelioma of the palate minor GS. 

Discussion/Conclusion: ME are rare tumors that typically manifest as slow-growing asymptomatic lesions. Other GS tumors such as pleomorphic adenoma should be considered in differential diagnoses of these lesions. 

References

Sperandio F, Giudice F, Pinto-Junior D, Sousa S. Myoepithelioma of the Soft Palate: a Case Report Giving Special Attention to the Differential Diagnosis. J Oral Maxillofac Res. 2011 Apr 1;2(1):e4. doi: 10.5037/jomr.2011.2104.

Barnes L, Appel BN, Perez H, Moneim El-Attar A. Myoepitheliomas of the head and neck: Case report and review. J Surg Oncol. 1985 Jan;28(1):21-8. doi:10.1002/jso.2930280107.

Cardesa A, Alos L. Myoepithelioma. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. Pathology and Genetics of Head and Neck Tumors. Lyon, France: IARC Press; 2005. pp. 259–260. (World Health Organizartion Classification of Tumors).

Lee MW, Nam SY, Choi HJ, Choi JH, Moon KC, Koh JK. Myoepithelioma of parotid gland presenting as infra-auricular subcutaneous mass. J Cutan Pathol. 2005 Mar;32(3):240-4. doi: 10.1111/j.0303-6987.2005.00293.x.

Hiwatashi A, Matsumoto S, Kamoi I, Yamashita H, Nakashima A. Imaging features of myoepithelioma arising from the hard palate: A case report. Acta Radiol. 2000 Sep;41(5):417-9. doi: 10.1080/028418500127345839.

Sheldon WH. So-called mixed tumors of the salivary glands. Arch Pathol. 1943; 35:1-20.

Duarte D, David L, Pais Clemente M. Mioepitelioma Plasmocitóide do Palato - Caso Clínico. Acta Otorrinolaringológica Gallega - sgorl. 1994 Mai; 1: 45-48.

Bolzoni A, Pianta L, Farina D, Nicolai P. Benign myoepithelioma of the lacrimal gland: report of a case. Eur Arch Otorhinolaryngol. 2005 Mar;262(3):186-8. doi:10.1007/s00405-004-0787-z.

Di Palma S, Guzzo M. Malignant myoepithelioma of salivary glands: Clinicopathological features of ten cases. Virchows Arch A Pathol Anat Histopathol. 1993;423(5):389-96. doi: 10.1007/bf01607152.

Waldron CA. Mixed tumor (pleomorphic adenoma) and myoepithelioma. In: Ellis Gary L, Auclair Paul L, Gnepp Douglas R. Surgical Pathology of the Salivary Glands. Philadelphia: Saunders; 1991. pp. 165-86.

Dardick I. Myoepithelioma: Definitions and Diagnostic Criteria. Ultrastruct Pathol. 1995 Sep-Oct;19(5):335-45. doi:10.3109/01913129509021906.

Yadav AK, Nadarajah J, Chandrashekhara SH, Tambade VD, Acharya S. Myoepithelioma of the soft palate: a case report. Case Rep Otolaryngol. 2013;2013:642806. doi: 10.1155/2013/642806.

Ellis Gary L, Auclair Paul L. Epithelial neoplasms. In: Ellis GL, Auclair PL, editors. Tumors of the Salivary Glands. Ann Arbor, Michigan, Estados Unidos: ARP Press; 2008. pp. 123–133.

Sciubba JJ, Brannon RB. Myoepithelioma of salivary glands: Report of 23 cases. Cancer. 1982 Feb 1;49(3):562-72. Doi.org/10.1002/1097-0142(19820201)49:3<562::aid-cncr2820490328>3.0.co;2-6.

Weitzel M, Cohn JE, Spector H. Myoepithelioma of the Parotid Gland: A Case Report with Review of the Literature and Classic Histopathology. Case Rep Otolaryngol. 2017;2017:6036179. doi: 10.1155/2017/6036179.

Published

2020-03-11

How to Cite

Borges da Costa, J., Pereira, D. A., Santos, J., Duarte, D., & Lopes, G. (2020). Myoepithelioma of the Hard Palate - A Case report. Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery, 57(3), 111–115. https://doi.org/10.34631/sporl.786

Issue

Section

Case Report