Sinonasal melanoma: A retrospective study

Authors

  • Ana Campos Interno de Formação Específica de Otorrinolaringologia, Serviço de Otorrinolaringologia do Hospital CUF Infante Santo, Portugal
  • Gustavo Almeida Interno de Formação Específica de Otorrinolaringologia, Serviço de Otorrinolaringologia do Hospital Egas Moniz, Portugal
  • João Órfão Interno de Formação Específica de Otorrinolaringologia, Serviço de Otorrinolaringologia do Hospital Prof. Doutor Fernando Fonseca, Portugal
  • Sara Custodio Interno de Formação Específica de Otorrinolaringologia, Serviço de Otorrinolaringologia do Hospital Egas Moniz, Portugal
  • Cristina Caroça Especialista em Otorrinolaringologia, Serviço de Otorrinolaringologia do Hospital CUF Infante Santo, Portugal
  • Ricardo Pacheco Assistente Hospitalar Graduado de Otorrinolaringologia, Serviço de Otorrinolaringologia do Instituto Português de Oncologia de Lisboa Francisco Gentil, Portugal
  • Pedro Montalvão Assistente Hospitalar Graduado Sénior de Otorrinolaringologia, Serviço de Otorrinolaringologia do Instituto Português de Oncologia de Lisboa Francisco Gentil, Portugal
  • Miguel Magalhães Director de Serviço Hospitalar, Serviço de Otorrinolaringologia do Instituto Português de Oncologia de Lisboa Francisco Gentil, Portugal

DOI:

https://doi.org/10.34631/sporl.861

Keywords:

sinonasal melanoma, natural history, treatment, survival

Abstract

Objective: To describe the natural history, treatment and prognosis of patients with the diagnosis of sinonasal melanoma in a Portuguese oncological referral center. 

Study design: Retrospective database review. 

Material & methods: The clinical records of patients with the diagnosis of sinonasal mucosal melanoma who underwent treatment between 2005 and 2016 in Instituto Português de Oncologia de Lisboa Francisco Gentil were reviewed. 

Results: A total of 19 patients were included, 12 female and 7 male. Mean age was 73 years and the more frequent initial symptoms were nasal obstruction and nasal bleeding. All patients had involvement of the nasal fossae and 53% had simultaneous sinus involvement. The maxillary sinus was the most affected (53%). Most patients had T4a (53%) and were treated with surgery (83%). A total of 64% patients had recurrence, 32% local and 32% metastatic, most frequently in lung and liver. Overall survival after recurrence was 5 months and disease free survival was 24 months. The median overall survival was 34 months and the 3 year overall survival was 47%. The overall survival at 3 years was significantly diminished in advanced T stages (P=0.01). 

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Published

2021-03-07

How to Cite

Campos, A., Almeida, G., Órfão, J. ., Custodio, S., Caroça, C., Pacheco, R., Montalvão, P., & Magalhães, M. (2021). Sinonasal melanoma: A retrospective study. Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery, 59(1), 63–69. https://doi.org/10.34631/sporl.861

Issue

Vol. 59 No. 1 (2021): March

Section

Original Article

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