Bilateral vocal fold paralysis: causes and treatment – 12 years’ experience
DOI:
https://doi.org/10.34631/sporl.2183Keywords:
bilateral vocal fold paralysis, rare causes stridor, hypocalcaemia, hypothyroidism, neurosyphilis, posterior cordotomy, tracheostomyAbstract
Aim: To analyse the cases of bilateral vocal fold paralysis (BVFP) diagnosed by the ENT department at Hospital Garcia de Orta. To emphasize rare causes of this entity and its treatment.
Study design: Retrospective study of BVFP cases diagnosed between January 2011 and December 2022.
Materials and methods: Inclusion criteria: diagnosis of BVFP by an ENT with videonasolaryngoscopy documentation. Patients with pharyngolaryngeal neoplasia and insufficient records were excluded.
Results: 109 patients were diagnosed with BVFP. The mean age at diagnosis time was 67 years. The presenting symptoms were: acute high dyspnoea in 92.7%, dysphonia in 19.3% and dysphagia in 7.3%. Rare causes were diagnosed: degenerative neurological diseases, neoplasms (thymus, oesophagus, lung, central nervous system), newly brain metastasis, hypocalcaemia, hypothyroidism, neurosyphilis, acute hepatitis B, meningitis and rheumatoid arthritis. 78% patients were approached surgically: tracheostomy, posterior cordotomy using LASER® and vocal cord lateralization.
Conclusions: The etiological investigation with imaging exams and analytical evaluation allowed the diagnosis of rare causes of BVFP. In some cases, correction of the underlying cause has allowed reversion of vocal fold paralysis.
References
Marina MB, Marie JP, Birchall MA. Laryngeal reinnervation for bilateral vocal fold paralysis. Curr Opin Otolaryngol Head Neck Surg. 2011 Dec;19(6):434-8. doi: 10.1097/MOO.0b013e32834c7d30.
Rosenthal LHS, Benninger MS, Deeb RH. Vocal fold immobility: a longitudinal analysis of etiology over 20 years. Laryngoscope. 2007 Oct;117(10):1864-70. doi: 10.1097/MLG.0b013e3180de4d49.
Lewis AF, Carron JD, Vedanarayanan V. Congenital bilateral vocal fold paralysis and Charcot-Marie-Tooth disease. Ann Otol Rhinol Laryngol. 2010 Jan;119(1):47-9. doi: 10.1177/000348941011900109.
Czesak MA, Osuch-Wójcikiewicz E, Niemczyk K. Methods of surgical treatment of bilateral vocal fold paralysis. Endokrynol Pol. 2020;71(4):350-358. doi: 10.5603/EP.a2020.0042.
Young VN, Rosen CA. Arytenoid and posterior vocal fold surgery for bilateral vocal fold immobility. Curr Opin Otolaryngol Head Neck Surg. 2011 Dec;19(6):422-7. doi: 10.1097/MOO.0b013e32834c1f1c.
Lichtenberger G. Endo-extralaryngeal needle carrier instrument. Laryngoscope. 1983 Oct;93(10):1348-50. doi: 10.1002/lary.1983.93.10.1348.
Chen EY, Inglis AF. Bilateral vocal cord paralysis in children. Otolaryngol Clin North Am. 2008 Oct;41(5):889-901, viii. doi: 10.1016/j.otc.2008.04.003.
Takano S, Nito T, Tamaruya N, Kimura M, Tayama N. Single institutional analysis of trends over 45 years in etiology of vocal fold paralysis. Auris Nasus Larynx. 2012 Dec;39(6):597-600. doi: 10.1016/j.anl.2012.02.001.
Nitschke C, Ghadban T, Izbicki J, Grotelüschen R. Hypocalcemia as an important differential diagnosis in patients suffering from stridor following thyroidectomy. Clin Case Rep. 2020 Nov 19;9(1):470-472. doi: 10.1002/ccr3.3559.
Chang M, Khoo JBK, Tan HK. Reversible recurrent laryngeal nerve palsy in acute thyroiditis. Singapore Med J. 2012 May;53(5):e101-3.
Deviditis RA, Coelho LS. Vocal fold paralysis in subacute thyroiditis. Braz J Otorhinolaryngol. 2007 Jan-Feb;73(1):138. doi: 10.1016/s1808-8694(15)31141-1.
Malik A, Abdullah M, Chaudhry M, Murtaza A, Kanwal A. Unilateral vocal cord paralysis in a patient with acute viral hepatitis. Cureus. 2021 Feb 17;13(2):e13399. doi: 10.7759/cureus.13399.
Dupuch V, Saroul N, Aumeran C, Pastourel R, Mom T, Gilain L. Bilateral vocal cord abductor paralysis associated with primary herpes simplex infection: a case report. Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Oct;129(5):272-4. doi: 10.1016/j.anorl.2012.02.004
Pelletier G, Elghozi D, Trépo C, Laverdant C, Benhamou JP. Mononeuritis in acute viral hepatitis. Digestion. 1985;32(1):53-6. doi: 10.1159/000199217.
Asha'ari ZA, Razali MS, Ahmad RA. Bilateral vocal cord palsy as the sole presentation of acquired syphilis. Malays J Med Sci. 2010 Apr;17(2):56-60.
Antal GM, Lukehart SA, Meheus AZ. The endemic treponematoses. Microbes Infect. 2002 Jan;4(1):83-94. doi: 10.1016/s1286-4579(01)01513-1.
Clack ZA, Anand KJS, Fortenberry, JD, Chambliss CR. Bilateral Vocal Cord Paralysis After Meningitis Due to Streptococcus pneumoniae. South Med J. 1998 Jul;91(7):660-2. doi: 10.1097/00007611-199807000-00010.
Eddaoudi M, Rostom S, Amine B, Bahiri R. The involvement of vocal cords in rheumatoid arthritis: a clinical case. Pan Afr Med J. 2019 Oct 21:34:102. doi: 10.11604/pamj.2019.34.102.20490.
Landouré G, Cissé L, Touré BA, Yalcouyé A, Coulibaly T, Karambé M. et al. Neurological complications in subjects with sickle cell disease or trait: genetic results from Mali. Glob Heart. 2017 Jun;12(2):77-80. doi: 10.1016/j.gheart.2017.01.014.
Blumin JH, Berke GS. Bilateral Vocal Fold Paresis and Multiple System Atrophy. Arch Otolaryngol Head Neck Surg. 2002 Dec;128(12):1404-7. doi: 10.1001/archotol.128.12.1404.
Segas J, Stavroulakis P, Manolopoulos L, Yiotakis J, Adamopoulos G. Management of bilateral vocal fold paralysis: experience at the University of Athens. Otolaryngol Head Neck Surg. 2001 Jan;124(1):68-71. doi: 10.1067/mhn.2001.111599.
Tachimori Y, Kato H, Watanabe H, Ishikawa T, Yamaguchi H. Vocal cord paralysis in patients with thoracic esophageal carcinoma. J Surg Oncol. 1995 Aug;59(4):230-2. doi: 10.1002/jso.2930590406.
Li Y, Garrett G, Zealear D. Current treatment options for bilateral vocal fold paralysis: a State-of-the-Art Review. Clin Exp Otorhinolaryngol. 2017 Sep;10(3):203-212. doi: 10.21053/ceo.2017.00199.
Chen X, Wan P, Yu Y, Li M, Xu Y, Huang P. et al. Types and timing of therapy for vocal fold paresis/paralysis after thyroidectomy: a systematic review and meta-analysis. J Voice. 2014 Nov;28(6):799-808. doi: 10.1016/j.jvoice.2014.02.003
Jackowska J, Sjogren EV, Bartochowska A, Czerniejewska-Wolska H, Piersiala K, Wierzbicka M. Outcomes of CO2 laser-assisted posterior cordectomy in bilateral vocal cord paralysis in 132 cases. Lasers Med Sci. 2018 Jul;33(5):1115-1121. doi: 10.1007/s10103-018-2478-9.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.