Solitary Neurofibroma of the larynx in adults
DOI:
https://doi.org/10.34631/sporl.992Keywords:
neurofibroma, neural tumor, larynx, laryngealAbstract
Neurofibromas are benign tumors with neural origin, most frequently found in neurofibromatosis. However, they can also occur as isolated lesions, which are extremely rare in the larynx. We present a case of a 56 years old patient who presented with complains of odynophagia, hoarseness, dysphagia and dyspnea. On otolaryngologic observation it was found a large pharyngolaryngeal mass compressing the airway, which led to perform a tracheotomy. The patient was submitted to surgical resection of the tumor and it was diagnosed with a solitary laryngeal neurofibroma. Due to the rarity of the disease, we present the first case identified in the Portuguese population and also perform a review of this entity in the adult, to contribute for a better understanding of the disease.
References
Liu J, Wong CF, Lim F, Kanagalingam J. Glottic neurofibroma in an elderly patient: a case report. J Voice. 2013 Sep;27(5):644-6. doi: 10.1016/j.jvoice.2013.02.002.
Shanmugaratnam K, Sobin LH. The world health organization histological classification of tumours of the upper respiratory tract and ear. A commentary on the second edition. Cancer. 1993 Apr 15;71(8):2689-97. doi: 10.1002/1097-0142(19930415)71:8<2689::aid-cncr2820710843>3.0.co;2-h.
Zhang L, Jiang J, Hu C, Yang H, Deng P, Li Y. Diagnosis and Management of Solitary Laryngeal Neurofibromas. Am J Med Sci. 2018 Jul;356(1):79-83. doi: 10.1016/j.amjms.2017.12.005.
Chinn SB, Collar RM, McHugh JB, Hogikyan ND, Thorne MC. Pediatric laryngeal neurofibroma: Case report and review of the literature. Int J Pediatr Otorhinolaryngol. 2014 Jan;78(1):142-7. doi: 10.1016/j.ijporl.2013.10.047.
Smith T. Solitary Neurofibroma of the larynx. Arch Otolaryngol. 1944; 39(2): 144–151. doi: 10.1001/archotol.1944.00680010155004.
Oliver KS, Diab AE, Abu-Jaudeh CN. Solitary Neurofibroma of the Larynx. Arch Otolaryngol. 1948 Feb;47(2):177-9. doi: 10.1001/archotol.1948.00690030186010.
Fisher GE, Odess JS. Solitary Neurofibroma of the larynx (report of two cases). Laryngoscope. 1949 Dec;59(12):1345-9. doi: 10.1288/00005537-194912000-00006.
Figi FA, Stark DB. Neurofibroma of the larynx Presentation of five cases. Laryngoscope. 1953 Jul;63(7):652-9. doi: 10.1288/00005537-195307000-00008.
Zobell DH. Massive neurofibroma of the larynx: Case report. Laryngoscope. 1964 Feb;74:233-40. doi: 10.1002/lary.5540740206.
Cummings CW, Montgomery WW, Balogh K Jr. Neurogenic Tumors of the Larynx. Ann Otol Rhinol Laryngol. 1969 Feb;78(1):76-95. doi: 10.1177/000348946907800107.
Martinez S, Hisa Y, Tatemoto K, Dejima K, Nishiyama Y, Masuda Y. Laser vestibulectomy for endolaryngeal neurofibroma. Otolaryngol Head Neck Surg. 1995 Oct;113(4):459-61. doi: 10.1016/s0194-5998(95)70085-4.
Puri R, Berry S, Srivastava G. Solitary neurofibroma of the larynx. Otolaryngol Head Neck Surg. 1997 Dec;117(6):713-4. doi: 10.1016/s0194-5998(97)70059-7.
Koc C, Luxenberger W, Humer U, Friedrich G. Bilateral ventricular neurofibroma of the larynx. J Laryngol Otol. 1996 Apr;110(4):385-6. doi: 10.1017/s0022215100133705.
Gstöttner M, Galvan O, Gschwendtner A, Neher A. Solitary subglottic neurofibroma: a report of an unusual manifestation. Eur Arch Otorhinolaryngol. 2005 Sep;262(9):705-7. doi: 10.1007/s00405-004-0886-x
Son HY, Shim HS, Kim JP, Woo SH. Synchronous plexiform neurofibroma in the arytenoids and neurofibroma in the parapharynx in a patient with non-neurofibromatosis: a case report. J Med Case Rep. 2013 Jan 10;7:15. doi: 10.1186/1752-1947-7-15.
Neurofibromatosis: Conference statement - National Institute of Health Consensus Development Conference. Arch Neurol. 1988 May;45(5):575-8. Doi: 10.1001/archneur.1988.00520290115023
Nakahira M, Nakatani H, Sawada S, Matsumoto S. Neurofibroma of the larynx in neurofibromatosis: preoperative computed tomography and magnetic resonance imaging. Arch Otolaryngol Head Neck Surg. 2001 Mar;127(3):325-8. doi: 10.1001/archotol.127.3.325.
Tanaka H, Patel U, Coniglio JU, Rubio A. Solitary subglottic neurofibroma: MR findings. AJNR Am J Neuroradiol.[Internet] 1997 Oct;18(9):1726-8. Available from: http://www.ajnr.org/content/ajnr/18/9/1726.full.pdf
Pulli RS, Coniglio JU. Subglottic nerve sheath tumor in a pediatric patient: Case report and literature review. Head Neck. 1997 Aug;19(5):440-4. doi: 10.1002/(sici)1097-0347(199708)19:5<440::aid-hed13>3.0.co;2-b.
Chen YW, Fang TJ, Li HY. A solitary laryngeal neurofibroma in a pediatric patient. Chang Gung Med J. [Internet] 2004 Dec;27(12):930-3. Available from: http://cgmj.cgu.edu.tw/2712/271210.pdf
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
