Sentinel lymph node biopsy in squamous cell carcinoma of the tongue

Authors

  • Marta Mariano Otorhinolaryngology Department, Centro Hospitalar Universitário de Lisboa Centra
  • Luís Castelhano Otorhinolaryngology Department, Centro Hospitalar de Lisboa Ocidental, Portugal
  • Marta Melo Otorhinolaryngology Department, Hospital Prof. Doutor Fernando Fonseca, Portugal
  • Susana Pereira Otorhinolaryngology Department, Centro Hospitalar Universitário de Lisboa Central, Portugal
  • Luís Oliveira Otorhinolaryngology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Portugal
  • Pedro Montalvão Otorhinolaryngology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Portugal
  • Miguel Magalhães Otorhinolaryngology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Portugal

DOI:

https://doi.org/10.34631/sporl.968

Keywords:

sentinel lymph node biopsy, squamous cell carcinoma, tongue

Abstract

Objective: Reporting the performance of sentinel lymph node biopsy (SLNB) in patients with squamous cell carcinoma (SCC) of the tongue.

Study design: Retrospective observational study.

Material and Methods: Clinical records from patients with SCC of the tongue cT1-2N0 submitted to SLNB were analysed. A sample of 23 patients was obtained. The gold standard for diagnosing lymph node metastasis was the histology of neck dissection specimens. The average follow up was 29.7 months.

Results: Forty-seven sentinel lymph nodes were obtained, 17% with SCC metastasis, from 26.1% of patients. Neck dissection was performed in 18 patients and 22.2% were positive for SCC metastasis. In this sample, SLNB had a sensitivity of 75% and a negative predictive value (NPV) of 83.3%.

Conclusion: SLNB showed high sensitivity and NPV in this sample. Increasing use of this technique will improve its performance and avoid unnecessary elective neck dissections.

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Published

2022-03-30

How to Cite

Mariano, M., Castelhano, L., Melo, M., Pereira, S., Oliveira, L., Montalvão, P., & Magalhães, M. (2022). Sentinel lymph node biopsy in squamous cell carcinoma of the tongue. Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery, 60(1), 23–27. https://doi.org/10.34631/sporl.968

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Original Article