Lingual thyroid: a case report and literature review
DOI:
https://doi.org/10.34631/sporl.1083Keywords:
thyroid gland, lingual thyroid, supraglottitisAbstract
The presence of ectopic thyroid tissue at the base of the tongue is called lingual thyroid. Most cases are asymptomatic, sometimes being diagnosed accidentally, for example, in the context of an upper respiratory infection. In this paper, we present the case of a 44-year-old female patient, with a history of hypothyroidism, who came to the emergency department with fever, odynophagia, dysphagia, and right otalgia. She had edema, purulent exudate and areas of necrosis on the lingual surface of the epiglottis, ventricular and arytenoid bands; a mass was found at the base of the tongue, in the midline, above the epiglottis, with normal-appearing mucosa. Cervical computed tomography confirmed the diagnosis of supraglottitis and showed a hyperdense nodular image with uptake of contrast product at the base of the tongue, consistent with lingual thyroid; in the usual topography of the thyroid, only a small nodular image was identified. The Tc99 scintigram confirmed the diagnosis of lingual thyroid, with a larger nodular image in the oropharynx and a small one in the thyroid topographic area.
References
Kumar V, Nagendhar Y, Prakash B, Chattopadhyay A, Vepakomma D. Lingual Thyroid Gland: Clinical evaluation and management. Indian J Pediatr. 2004 Dec;71(12):e62-4.
Arikan S, Gökalp D, Tuzcu A, Bahceci M, Bahceci S. An embryological cause of primer hypothyroidism, lingual thyroid. Turkish Journal of Endocrinology and Metabolism [Internet] 2006; 2: 49-52. Available from: https://www.turkjem.org/Content/files/sayilar/102/10-2-0_49-52.pdf.
Yoon JS, Won KC, Cho IH, Lee JT, Lee HW. Clinical Characteristics of Ectopic Thyroid in Korea. Thyroid. 2007 Nov;17(11):1117-21. doi: 10.1089/thy.2007.0004.
Shafer WG, Hine MK, Levy BM. Textbook of oral pathology. 4th ed. Philadelphia: W.B.Saunders, 1983. 917 p.
Okstad S, Mair IW, Sundsfjord JA, Eide TJ, Nordrum I. Ectopic thyroid tissue in the head and neck. J Otolaryngol. 1986 Feb;15(1):52-5. J Otolaryngol 1986;15:52-55.
Charles ND. Thyroid and whole-body imaging. In: The thyroid, 5th ed. Ed Ingbar and Braveman. Philadelphia: Lippincot; 1986. p. 458-78.
Nienas FW, Gorman CA, Devine KD, Woolner LB. Lingual thyroid: clinical characteristics of 15 cases. Ann Intern Med. 1973 Aug;79(2):205-10. doi: 10.7326/0003-4819-79-2-205.
Williams JD, Slupchinskij O, Sclafani AP, Douge C. Evaluation and management of the lingual thyroid gland. Ann Otol Rhinol Laryngol. 1996 Apr;105(4):312-6. doi: 10.1177/000348949610500414.
Kalan A, Tarik M. Lingual thyroid gland: clinical evaluation and comprehensive management. Ear Nose Throat J. 1999 May;78(5):340-1, 345-9.
van der Gaag RD, Drexhage HA, Dussault JH. Role of maternal immunoglobulins blocking TSH–induced thyroid growth in sporadic forms of congenital hypothyroidism. Lancet. 1985 Feb 2;1(8423):246-50. doi: 10.1016/s0140-6736(85)91028-1.
Cruz-Dardíz N, Rivera-Santana N, Torres-Torres M, Cintrón-Colón H, Lajud S, Solá-Sánchez E. et al. Lingual thyroid gland: it’s time for awareness. Endocrinol Diabetes Metab Case Rep. 2020 May 29;2020:EDM20-0026. doi: 10.1530/EDM-20-0026.
Amr B, Monib S. Lingual thyroid: a case report. Int J Surg Case Rep. 2011;2(8):313-5. doi: 10.1016/j.ijscr.2011.10.004.
Koc G, Taskaldiran I, Aslan Felek S, Saltabas MA, Omma T, Akbulut A. et al. Ectopic lingual thyroid presenting with massive hematemesis. Acta Endocrinol (Buchar). 2019 Apr-Jun;15(2):244-246. doi: 10.4183/aeb.2019.244.
Kumar S, Kumar D, Thirunavukuarasu R. Lingual thyroid-conservative management or surgery? A case report. Indian J Surg. 2013 Jun;75(Suppl 1):118-9. doi: 10.1007/s12262-012-0518-4.
Thomas G, Hoilat R, Daniels J, Kalagie W. Ectopic lingual thyroid: a case report. Int J Oral Maxillofac Surg. 2003 Apr;32(2):219-21. doi: 10.1054/ijom.2002.0311.
Rao K, Shenoy V, Kamath P, Gomati A. A case of lingual thyroid. Annals of Clinical Investigation [Internet] 2020 Apr 25; 1(1): 1002. Available from: http://www.remedypublications.com/open-access/a-case-of-lingual-thyroid-5875.pdf
Santangelo G, Pellino G, De Falco N, Colella G, D'Amato S, Maglione MG. et al. Prevalence, diagnosis and management of ectopic thyroid glands. Int J Surg. 2016 Apr;28 Suppl 1:S1-6. doi: 10.1016/j.ijsu.2015.12.043.
Kaushal D, Shakrawal N, Goyal A, Nair N, Verma A, Prakash D. Ectopic lingual thyroid: an entity not to be missed. Int J Mol Biol Open Access. 2019;4(4):132-133. doi: 10.15406/ijmboa.2019.04.00109.
Bayram F, Kulahli I, Yuce I, Gokçe C, Cagli S, Deniz K. Functional lingual thyroid as unusual cause of progressive dysphagia. Thyroid. 2004 Apr;14(4):321-4. doi: 10.1089/105072504323030997.
Sargin H, Kabacam G, Koseoullari O, Sanli A, Erdogan MF. Three cases of lingual thyroid and review of the literature. Turkish J Endocrinol and Metabol, 2003 (3):131-135.
Chiu TT, Su CY, Hwang CF, Chien CY, Eng HL. Massive bleeding from an ectopic lingual thyroid follicular adenoma during pregnancy. Am J Otolaryngol. 2002 May-Jun;23(3):185-8. doi: 10.1053/ajot.2002.123432.
Ramanathan R, Veerapandian J, Sundari S. Lingual thyroid with hypothyroidism in a child. Int J Contemp Pediatrics. 2019; 6 (4): 1747-1749. doi.org/10.18203/2349-3291.ijcp20192787.
Ibrahim N, Fadeyibi I. Ectopic thyroid: etiology, pathology and management. Hormones (Athens). 2011 Oct-Dec;10(4):261-9. doi: 10.14310/horm.2002.1317.
Hazarika P, Siddiqui SA, Pujary K, Shah P, Nayak DR, Balakrishnan R. Dual ectopic thyroid: a report of two cases. J Laryngol Otol. 1998 Apr;112(4):393-5. doi: 10.1017/s0022215100140563.
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