Aplicações da mitomicina-c em rinologia - Caso clínico e revisão da literatura
DOI:
https://doi.org/10.34631/sporl.340Palavras-chave:
Mitomicina-C, rinologia, atrésia choanal, cirurgia endoscópica naso-sinusalResumo
Objectivos: Rever a bibliografia no que concerne às aplicações da Mitomicina-C na área da Rinologia.
Métodos: Pesquisa no motor de busca PubMed. Apresenta-se, sumariamente um caso clínico do serviço de ORL-CCF do Hospital Garcia de Orta em que a Mitomicina-C foi utilizada como adjuvante na correcção cirúrgica de uma atrésia choanal unilateral.
Resultados: A mitomicina-C é um agente antiproliferativo que inibe o crescimento e proliferação fibroblástica. O sucesso do seu uso na prevenção da formação de tecido de granulação e cicatricial em cirurgia oftálmica estimulou a sua utilização nos vários domínios da Otorrinolaringologia.
Conclusões: No âmbito da Rinologia, a Mitomicina-C parece ter provas dadas de benefício aquando da sua aplicação nas dacriocistorrinostomias endoscópicas e de promissora na prevenção de sinéquias após cirurgia endoscópica naso-sinusal com o intuito de alargar os ostia naturais. A nível da correcção cirúrgica das atrésias choanais falta reunir evidência científica que suporte o seu uso de rotina.
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